Meniu
Asmeninė anketa Prisijungimas ir registracija
Atgal » » » 2020 » Spalio » 19

A new way to personalize treatments for prostate cancer

A new way to personalize treatments for prostate cancer

Rutgers researchers have discovered human gene markers that work together to cause metastatic prostate cancer—cancer that spreads beyond the prostate.

The study, published in the journal Nature Cancer, explored prostate cancer cells from people and mice and found a wide collaboration among 16 genes that leads to metastasis, which often leads to treatment challenges.

The gene markers identified can predict if a prostate cancer patient has a high probability of developing metastasis, including bone.

Prostate cancer is the second leading cause of cancer-related deaths among men in the United States with a five-year relative survival rate of near 100 percent when diagnosed early. Metastatic prostate cancer has a five-year survival rate of 30 percent. Current therapeutics like first- and next- generation anti-androgens that target male sex hormones alongside radiation, chemotherapy and others are not always effective, and it's impossible to predict which patients are at risk of developing the advanced late stage of the disease.

"People diagnosed with prostate cancer should now be screened for the protein markers discovered to help determine their risk of developing metastatic prostate cancer, which can help inform more personalized therapy," said Antonina Mitrofanova, an assistant professor at the Rutgers School of Health Professions and research member at Rutgers Cancer Institute of New Jersey. "Our results show that molecular profiling at the time of diagnosis can help inform more personalized therapy leading to better outcomes for those with this advanced form of disease."

Researchers say testing for these gene markers can also predict which patients will fail to respond to normally used androgen targeting therapies in metastatic disease and can decrease multiple treatment rounds for patients.

Researchers, in collaboration with Cory Abate-Shen's lab at Columbia University, have obtained a patent for their discovery and are looking to develop therapeutics and diagnostic tools.

  • by Rutgers University
  • Micrograph showing prostatic acinar adenocarcinoma (the most common form of prostate cancer) Credit: Wikipedia

Turite savo nuomone, (už ar, prieš) pasidalinkite su mumis, palikite komentarą, prisijunkite, rašykite bloge, pasirinkdami kategoriją. Pasidalinkite savo receptais, sveikatos patarimais, nutikimais, susidūrėte su paranormaliais, anomališkais ir kitais nekasdieniškais reiškiniais. Galite išversti iš užsienio kalbos, talpinkite su nuoroda. Laukiame Jūsų straipsnių, naujienų, apžvalgų ar istorijų!

Įvertink šį straipsnį. Prieš tai pakomentuodami, arba parašykite patys! Norėdami tobulėti, suteikiame jums galimybę įvertinti skaitomą PARANORMAL turinį. Norite sužinoti daugiau, sutikite gauti naujienas arba pasidalinkite spausdami .
Niekas neišdrįso palikti komentaro.
Būkite pirmi, kurie pasidalins savo nuomonėmis su kitais.
avatar
TAIP PAT SKAITYKITE:
01.12.2020 laikas 23:18 Legitimacy of Biden win buried by objective data

During the weeks following November 3, innumerable election experts and statistical analysts have pored over the voting data upon which former Vice President Joe Biden’s purported campaign victory ostensibly stands.

...

Skaityti daugiau

01.12.2020 laikas 23:05 Obama, Biden helped corrupt CCP-linked coronavirus testing firm come to the U.S.

During their occupation of the White House, Barack Obama and Joe Biden gave the green light to a Chinese Communist Party (CCP)-linked corporation to establish a presence in the United States where it is now trying to peddle Wuhan coronavirus (COVID-19) testing kits on Americans.

...

Skaityti daugiau

01.12.2020 laikas 23:05 Skeptical of voter fraud in 2020? Here’s your evidence.
Has anyone ever told you that “You can’t do it” and “You’re crazy” over and over? Perhaps they’ve told you this so many times, you’ve started to believe it yourself. This is what’s happening in our election today....

Skaityti daugiau

01.12.2020 laikas 20:49 10 paprastų aukštą kraujospūdį mažinančių produktų
Besiskundžiantiems padidėjusiu kraujospūdžiu ir sergantiems hipertenzija patariama vartoti produktų, kuriuose gausu kalio, nes kalis neutralizuoja žalingąjį druskos poveikį. Be to, naudinga vartoti produktų, kuriuose gausu magnio, vitamino C ir maistinių skaidulų....

Skaityti daugiau

01.12.2020 laikas 20:27 6 rudeniniai produktai, kurie organizme didina hemoglobino lygį

Žemas hemoglobino lygis būna todėl, kad organizme pernelyg mažai geležies. Norėdami padidinti hemoglobino lygį, rudenį gausiau vartokite sezoninių produktų.

Skaityti daugiau

01.12.2020 laikas 19:45 Kada jodas netinka gydyti skydliaukės ligas?
Jodas būtinas skydliaukės ligų profilaktikai, normaliam jos darbui, jei ji sveika.

Skaityti daugiau